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Tofacitinib for refractory uveitis and scleritis
Michael A Paley1,2, Humeyra Karacal3,2, P Kumar Rao3,2
1Department of Medicine, Saint Louis, MO, 63110, USA.
American Journal of Ophthalmology Case Reports
|December 25, 2018
Abstract
Purpose:
To report the successful use of tofacitinib in the treatment of refractory uveitis and scleritis.
Observations:
Two patients, one with scleritis and another with anterior and intermediate uveitis, presented with refractory disease after failure of multiple steroid-sparing therapies. Treatment with tofacitinib led to durable resolution of uveitis and scleritis.
Conclusions And Importance:
Tofacitinib is a potential novel treatment option for refractory, noninfectious inflammatory eye disease.
