Related Experiment Video
Updated: Jan 31, 2026
Robot-Assisted Kidney Transplantation
Published on: July 19, 2021
Phase Angle Is Associated With Handgrip Strength but Not With Sarcopenia in Kidney Transplantation Patients
Aline S Dos Reis1, Heitor O Santos1, Larissa S Limirio1
1School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais, Brazil.
Objectives:
Phase angle (PhA) is a cell health marker and has been associated with muscle mass and strength in non-kidney disease individuals. However, it is unknown whether PhA is a predictor of sarcopenia and its components in kidney transplantation patients. The aim of the present study was to associate PhA with sarcopenia and its components in kidney transplantation patients.
Design And Methods:
One hundred and twenty-nine kidney transplantation individuals were evaluated in a cross-sectional study. PhA and muscle mass were evaluated using bioelectrical impedance. Handgrip strength (HGS) was performed with a hand dynamometer and functional capacity with 4-m walk test. Sarcopenia was diagnosed according to the European Consensus Diagnostic Criteria for Sarcopenia. Participants were divided according to the PhA tercile, and 2 groups were evaluated: first versus second and third terciles, according to sex. The individuals in the first tercile had PhA values <5.8° and <6.2° for women and men, respectively.
Results:
Individuals in the lower tercile of PhA showed lower odds of having higher values of HGS (kg; odds ratio [OR] = 0.89; 95% confidence interval [CI]: 0.82-0.97) and higher odds to have low HGS (OR = 5.97; 95% CI: 1.05-33.98). However, PhA was not associated with sarcopenia (OR = 1.95; 95% CI: 0.71-5.39), low muscle mass index (OR = 1.17; 95% CI: 0.41-3.36), and low functional capacity (OR = 2.47; 95% CI: 0.45-13.48).
Conclusion:
PhA was associated with HGS but not with sarcopenia and its other components. These results suggest that PhA can be used as a possible predictor of muscle strength in kidney transplantation patients.
Related Concept Videos
01:28Kidney Transplant I: Introduction
01:26Kidney Transplant II: Surgical Procedure
01:16Kidney Transplant III: Nursing Management
02:31Phase Transitions
01:45Kidney Structure
03:05Acid Strength and Molecular Structure
In the absence of any leveling effect, the acid strength of binary compounds of hydrogen with nonmetals (A) increases as the H-A bond strength decreases down a group in the periodic table. For group 17, the order of increasing acidity is HF < HCl < HBr < HI. Likewise, for group 16, the order of increasing acid strength is H2O < H2S < H2Se < H2Te. Across a row in the periodic table, the acid strength of binary hydrogen compounds increases with increasing...