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Volatolomics: A broad area of experimentation
S Giannoukos1, A Agapiou2, B Brkić3
1Laboratory of Atmospheric Chemistry, Paul Scherrer Institute (PSI), 5232 Villigen, Switzerland; University of Liverpool, Department of Electrical Engineering and Electronics, Liverpool L69 3GJ, UK.
Summary
Volatile metabolomics, or volatolomics, analyzes compounds from organisms for applications in disease diagnosis, environmental monitoring, and security. This review covers recent advances in volatile organic compound (VOC) analysis and detection technologies.
Area of Science:
- Analytical Chemistry
- Metabolomics
- Biotechnology
Background:
- Chemical analysis of metabolic compounds is a rapidly advancing scientific field.
- Volatile metabolomics (volatolomics) offers diverse applications across multiple disciplines.
- Volatile organic compounds (VOCs) are key indicators of biological activity.
Purpose of the Study:
- To provide an overview of recent advancements in volatolomics.
- To highlight the broad range of applications for volatolomics.
- To discuss both bench-top and portable detection technologies.
Main Methods:
- Review of recent literature on volatolomics.
- Focus on volatile organic compounds (VOCs) from biological sources.
- Analysis of detection and monitoring systems for VOCs.
Main Results:
- Volatolomics has significant applications in biomedical research, toxicology, forensics, and safety.
- VOCs from microorganisms, insects, plants, and humans are crucial for chemical information fusion.
- Both laboratory-based and field-deployable technologies are essential for volatolomics.
Conclusions:
- Volatolomics is a powerful tool for understanding biological processes and their environmental impact.
- The integration of chemical information from VOCs enhances diagnostic and monitoring capabilities.
- Advancements in technology are expanding the accessibility and utility of volatolomics.
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