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Updated: Jan 31, 2026

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Organocatalyzed Intermolecular Asymmetric Allylic Dearomatization of Both α- and β-Naphthols
Binmiao Yang1, Xuejie Zhai1, Shubo Feng1
1Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology , Yunnan University , Kunming 650091 , China.
Abstract:
The first highly stereoselective intermolecular catalytic asymmetric dearomatization (CADA) of α-naphthols through C-C formation and the first asymmetric allylic dearomatization of naphthols by chiral organocatalysis have been achieved. These new and complete atom-economic reactions provide enantioriched α- and β-naphthalenones bearing an all-carbon quaternary center.
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