Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Decreasing Function01:27

Decreasing Function

290
A decreasing function describes a relationship where the output consistently declines as the input increases. This means that for any two input values, if one is greater than the other, the corresponding output is smaller. Mathematically, a function f is decreasing on an interval I if for every x1 < x2​ in I, f (x1) > f (x2). This type of behavior is visually identified on a graph that slopes downward from left to right.The nature of a function can be analyzed by calculating...
290
Decreased Body Temperature01:29

Decreased Body Temperature

1.1K
A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
1.1K
Decreased pulse rate01:14

Decreased pulse rate

900
Bradycardia is a medical condition in which the heart rate is slower than normal. It occurs when the heart's natural pacemaker, the sinus node, generates slower electrical impulses than the standard rhythm. In adults, bradycardia is diagnosed when the pulse rate falls below 60 beats per minute, indicating a deviation from the normal heart rate range.
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with...
900
Leveling Effect01:29

Leveling Effect

1.4K
In acid-base chemistry, the leveling effect refers to the limitation imposed by the solvent on the strength of acids and bases in solution. When a base stronger than the solvent's conjugate base is used, it deprotonates the solvent until the base is entirely consumed, making it ineffective against weaker acids. Conversely, an acid stronger than the solvent's conjugate acid protonates the solvent until the acid is depleted, rendering it ineffective against weaker bases. Essentially, the...
1.4K
High-Level and Low-Level Awareness01:19

High-Level and Low-Level Awareness

743
Controlled processes in human consciousness represent high-alert mental states where individuals deliberately focus their attention on achieving specific goals. Controlled processes can be seen in situations like mastering new technology, where a person might become so absorbed that they ignore surrounding distractions. Such processes involve selective attention, requiring one to concentrate on particular elements of experience while disregarding others. These are governed by executive...
743
Levels of Organization01:09

Levels of Organization

140.7K
Biological organization is the classification of biological structures, ranging from atoms at the bottom of the hierarchy to the Earth's biosphere. Each level of the hierarchy represents an increase in complexity that builds upon the previous level.
Molecules Are Composed of Atoms, and Biomolecules Are Assembled from Molecules:
The most basic levels include atoms, molecules, and biomolecules. Atoms, the smallest unit of ordinary matter, are composed of a nucleus and electrons. Molecules...
140.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Iron-mediated ferroptosis impairs CAR-T cell function and antitumor efficacy.

Nature cancer·2026
Same author

Breaking the Adsorption Seesaw Via Asymmetric Pt-M Sites for PET Electro-Upcycling.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Epidemiological trends and burden of gout in China and the European Union: a GBD 2023 and Mendelian randomization study.

Clinical rheumatology·2026
Same author

DASR-Net: dual-attention scattering restoration network for imaging in turbid media via weakly supervised learning.

Optics express·2026
Same author

Bacterial endosymbionts initiate morphogenesis of symbiotic organs at specific locations in auchenorrhynchan insects of Hemiptera.

Insect science·2026
Same author

Suppression of Nr1d1/Bnip3-dependent mitophagy by notch signaling aggravates inflammatory response in RSV-infected mice lungs.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]·2026
Same journal

Toxicity evaluation and anti-ischemic stroke activity of selected natural extracts in zebrafish.

Biomedical reports·2026
Same journal

Association between tidal volume and mortality in patients without acute respiratory distress syndrome: A systematic review and meta-analysis.

Biomedical reports·2026
Same journal

Clinical and pathological analysis of pediatric patients with primary pulmonary tumors at a single center.

Biomedical reports·2026
Same journal

Cariprazine-induced obsessive-compulsive symptoms in a patient with bipolar II disorder: A case report.

Biomedical reports·2026
Same journal

IL-6/STAT3 signaling pathway-mediated apoptosis induced by medical ozone water in liver cancer: A mechanistic study.

Biomedical reports·2026
Same journal

Exploring the mechanisms of baicalin in diabetic cardiomyopathy: Insights from network pharmacology and experimental validation.

Biomedical reports·2026
See all related articles

Related Experiment Video

Updated: Jan 31, 2026

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
09:31

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography

Published on: January 27, 2023

1.6K

Phototherapy is associated with the decrease in serum globulin levels in neonatal hyperbilirubinemia.

Junwen Zheng1, Cong Wei1, Meng Zhao1

  • 1Department of Pediatrics and Neonatology, Children's Digital Health and Data Center, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, P.R. China.

Biomedical Reports
|December 28, 2018
PubMed
Summary
This summary is machine-generated.

Phototherapy significantly decreased serum globulin (GLB) levels in infants with neonatal hyperbilirubinemia. This reduction was more pronounced in older infants and when combined with intravenous albumin (IVALB) therapy.

Keywords:
hyperbilirubinemiaintravenous immunoglobulineonatesphototherapyserum globulin

More Related Videos

Culturing Microglia from the Neonatal and Adult Central Nervous System
11:28

Culturing Microglia from the Neonatal and Adult Central Nervous System

Published on: August 9, 2013

28.9K
Daily Phototherapy with Red Light to Regulate Candida albicans Biofilm Growth
11:06

Daily Phototherapy with Red Light to Regulate Candida albicans Biofilm Growth

Published on: April 23, 2019

8.2K

Related Experiment Videos

Last Updated: Jan 31, 2026

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
09:31

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography

Published on: January 27, 2023

1.6K
Culturing Microglia from the Neonatal and Adult Central Nervous System
11:28

Culturing Microglia from the Neonatal and Adult Central Nervous System

Published on: August 9, 2013

28.9K
Daily Phototherapy with Red Light to Regulate Candida albicans Biofilm Growth
11:06

Daily Phototherapy with Red Light to Regulate Candida albicans Biofilm Growth

Published on: April 23, 2019

8.2K

Area of Science:

  • Neonatal Medicine
  • Pediatric Gastroenterology
  • Biochemistry

Background:

  • Phototherapy is a common treatment for neonatal hyperbilirubinemia.
  • Previous research suggests a potential link between phototherapy and later immune disorders.
  • The impact of phototherapy on serum globulin (GLB) levels in neonates requires further investigation.

Purpose of the Study:

  • To evaluate the effect of phototherapy on serum globulin (GLB) levels in infants with neonatal hyperbilirubinemia.
  • To assess GLB levels as a risk factor in neonatal hyperbilirubinemia treatment.
  • To determine if age influences the decrease in GLB levels during phototherapy.

Main Methods:

  • A cohort of 430 full-term infants with neonatal hyperbilirubinemia was studied.
  • Infants received phototherapy, intravenous albumin (IVALB), or both.
  • Serum total bilirubin (TSB), albumin (ALB), and GLB levels were measured before and after treatment.

Main Results:

  • Phototherapy significantly reduced TSB levels (P<0.001).
  • A significant decrease in GLB levels was observed, particularly in infants older than 16 days.
  • Combined phototherapy and IVALB treatment led to a greater decrease in GLB levels (P<0.001).

Conclusions:

  • Phototherapy is associated with a decrease in serum GLB levels in neonates with hyperbilirubinemia.
  • The decrease in GLB levels is more significant in older infants and is enhanced by IVALB treatment.
  • Further research is warranted to understand the long-term implications of these GLB level changes.