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Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers
Published on: September 19, 2022
[Analysis of photosensitizer gel penetration through the teeth structure]
O A Zorina1, E K Krechina2, Z M Abaev3
1Central Research Institute of Dental and Maxillofacial Surgery of Ministry of Health of the Russian Federation, Moscow, Russia; I.M. Sechenov First Moscow State Medical University, Moscow, Russia.
Abstract:
As a result of the studies carried out on 20 extracted frontal teeth it was reliably shown that after 10 minutes the concentration of the photosensitizer in enamel at full depth reached values sufficient for performing photodynamic teeth whitening. At the same time, the penetration of the photosensitizer into the deep layers of dentin was not detected which allows to carry out the photodynamic bleaching procedure only within the enamel and enamel-dentine boundary, thus not affecting the pulp of the tooth.
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