Where's the Beef?: How Much Can We Skimp on Pharmacokinetic-Pharmacodynamic Data?

Thomas K Henthorn¹, Erik Olofsen

• ¹From the Department of Anesthesiology, University of Colorado School of Medicine, Aurora, CO (T.K.H.) Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO (T.K.H.) Department of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands (E.O.).