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[Evaluation of a screening test for urinary infection]
A Audurier1, J C Burdin, H Darbas
1Laboratoire de Bactériologie, Hôpital Trousseau, Centre Hospitalier Universitaire de Tours, France.
Pathologie-Biologie
|September 1, 1988
Summary
This study evaluated reagent strips for detecting urinary tract infections (UTIs) in adults. The combination of nitrite and leukocyte tests showed high accuracy in ruling out infections, making it a useful screening tool.
Area of Science:
- Clinical diagnostics
- Microbiology
- Urology
Context:
- Urinary tract infections (UTIs) are common, necessitating efficient diagnostic methods.
- Rapid screening tools can aid in timely diagnosis and treatment.
- Evaluating diagnostic accuracy is crucial for clinical practice.
Purpose:
- To assess the diagnostic performance of a specific reagent strip (Multistix-8 SG) for UTI screening.
- To determine the sensitivity, specificity, and predictive values of the reagent strip tests.
- To evaluate the utility of the reagent strip in ruling out non-infected urine samples.
Summary:
- A clinical study analyzed 2,183 adult urine specimens, with 340 confirmed infections.
- The reagent strip's performance was measured using sensitivity, specificity, and predictive values.
- A negative predictive value of 97.5% for nitrites and leukocytes suggests high reliability in excluding infections.
Impact:
- The reagent strip, particularly the nitrite and leukocyte combination, can effectively screen for UTIs.
- This diagnostic tool can help reduce unnecessary laboratory investigations for non-infected urine.
- Findings support the integration of reagent strips into clinical workflows for UTI assessment.