Anemia profile in patients with congestive heart failure a hospital based observational study

Himanshu Arora1, J P S Sawhney1, Ashwani Mehta1

  • 1Department of Cardiology, Sir Ganga Ram Hospital, New Delhi 110060, India.

Indian Heart Journal
|January 1, 2019
PubMed

Insights

Iron deficiency is common in Indian heart failure patients, affecting over half of those studied. Many patients without anemia also showed iron deficiency, highlighting its prevalence.

Area of Science:

  • Cardiology
  • Nutritional Science
  • Internal Medicine

Background:

  • Iron deficiency (ID) is an emerging concern in congestive heart failure (CHF).
  • ID is a potential therapeutic target in CHF patients.
  • High prevalence of ID is hypothesized in the Indian population with CHF.

Purpose of the Study:

  • To investigate the prevalence of iron deficiency in Indian patients with congestive heart failure.
  • To assess the co-occurrence of B12 and folate deficiencies in this patient group.

Main Methods:

  • A cohort of 275 congestive heart failure patients was selected.
  • Laboratory evaluations included hemoglobin, serum iron, transferrin, ferritin, B12, and folate levels.

Main Results:

  • Out of 275 patients, 76.7% were anemic and 53.8% had iron deficiency.
  • Iron deficiency was found in 61.61% of anemic patients and 28.12% of non-anemic patients.
  • B12 and folate deficiencies were less prevalent, affecting 12.7% and 5.1% of the total cohort, respectively.

Conclusions:

  • Iron deficiency is highly prevalent in Indian patients with congestive heart failure.
  • A significant number of patients without anemia were also iron deficient.
  • B12 and folate deficiencies were less common contributors to the studied conditions.
Abstract

Related Concept Videos

Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
920
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
3.6K
Heart Failure I: Introduction01:27

Heart Failure I: Introduction

Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
882
Hospitals-II00:59

Hospitals-II

Hospitals provide inpatient and outpatient services. Inpatient services provide care to patients that stay in the hospital for an extended period, ranging from days to months. Examples of inpatient services include intensive care units, hospital wards, or surgeries. Outpatient services provide care to patients who come to a hospital for a diagnostic or treatment but do not stay overnight —for example, diagnostic tests, surgical procedures, or health education.
Nurses that work in...
1.2K
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
336
Heart Failure Drugs: Diuretics01:22

Heart Failure Drugs: Diuretics

Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
966