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Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis
Published on: June 30, 2023
Anemia profile in patients with congestive heart failure a hospital based observational study
Himanshu Arora1, J P S Sawhney1, Ashwani Mehta1
1Department of Cardiology, Sir Ganga Ram Hospital, New Delhi 110060, India.
Insights
Iron deficiency is common in Indian heart failure patients, affecting over half of those studied. Many patients without anemia also showed iron deficiency, highlighting its prevalence.
Area of Science:
- Cardiology
- Nutritional Science
- Internal Medicine
Background:
- Iron deficiency (ID) is an emerging concern in congestive heart failure (CHF).
- ID is a potential therapeutic target in CHF patients.
- High prevalence of ID is hypothesized in the Indian population with CHF.
Purpose of the Study:
- To investigate the prevalence of iron deficiency in Indian patients with congestive heart failure.
- To assess the co-occurrence of B12 and folate deficiencies in this patient group.
Main Methods:
- A cohort of 275 congestive heart failure patients was selected.
- Laboratory evaluations included hemoglobin, serum iron, transferrin, ferritin, B12, and folate levels.
Main Results:
- Out of 275 patients, 76.7% were anemic and 53.8% had iron deficiency.
- Iron deficiency was found in 61.61% of anemic patients and 28.12% of non-anemic patients.
- B12 and folate deficiencies were less prevalent, affecting 12.7% and 5.1% of the total cohort, respectively.
Conclusions:
- Iron deficiency is highly prevalent in Indian patients with congestive heart failure.
- A significant number of patients without anemia were also iron deficient.
- B12 and folate deficiencies were less common contributors to the studied conditions.
Objectives:
Iron deficiency (ID) is an emerging problem in patients with congestive heart failure (CHF) and can be a potential therapeutic target. As ID is highly prevalent in the society, it is hypothesized that Indian patients with CHF have high prevalence of ID.
Methods:
CHF patients (n = 275) were selected and underwent laboratory evaluation including hemoglobin concentration, serum iron, transferrin, ferritin, B12 and folate level.
Results:
Two hundred and seventy-five patients with heart failure (mean age - 62.72, mean Hb- 10.54 g/dl, 188 males [68.36%] and 87 females [31.64%]) were enrolled in the study. 211 out of 275 (76.7%) were found to be anemic. Out of 275 patients. 148 (53.8%) were diagnosed with iron deficiency. 12.7% (n = 35) were B12 deficient and 5.1% (n = 14) were folate deficient. In the anemic group, ID was present in 130 patients (61.61%), B12 deficiency in 32 patients (15.16%) and folate deficiency in 12 patients (5.68%). In the group of patients without anemia, ID was present in 18 patients (28.12%) while B12 and folate deficiency was present in 3 (4.68%) and 2 (3.12%) patients, respectively.
Conclusion:
Iron deficiency is present in substantial number while B12 and folate account for a few number of cases. Substantial number of patients without anemia were found to be iron deficient.
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