Related Experiment Video
Updated: Jan 31, 2026
Investigating the Relationship between Sea Surface Chlorophyll and Major Features of the South China Sea with Satellite Information
Published on: June 13, 2020
Predictors of thyroxine replacement following hemithyroidectomy in a south east Asian cohort
Peng Ng1, Cheryl Ho1, Wee Boon Tan2
1Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Background:
Thyroxine replacement following a hemithyroidectomy is not commonly discussed during consent for the procedure as the risk of hypothyroidism is perceived to be low.
Methods:
Retrospective review of 901 patients who underwent hemithyroidectomy at a tertiary referral institution during the period January 2000 to December 2015. The main outcome studied was the overall incidence of hypothyroidism and the associated risk factors.
Results:
Hypothyroidism developed in 123 (13%) patients and 94 patients (10%) required hormone supplementation over a mean follow up of 21 months (range 1-168 months). Preoperative TSH of more than 2.5 was seen in 38 of 123 (31%) of patients. Presence of diffuse thyroiditis was the only independent risk factor on multivariate analysis (P = 0.002) found to be associated with the development of hypothyroidism.
Conclusion:
After thyroid lobectomy, approximately one in 10 patients requiring thyroid hormone treatment for hypothyroidism. Presence of diffuse thyroiditis is a significant risk factor for hypothyroidism.
More Related Videos
Related Concept Videos
01:30Continuous Renal Replacement Therapy
01:26Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy
01:50Cross-Sectional Research
02:39Gene Flow
01:16In-vitro Mutagenesis
02:46Crystal Field Theory - Tetrahedral and Square Planar Complexes
Crystal field theory (CFT) is applicable to molecules in geometries other than octahedral. In octahedral complexes, the lobes of the dx2−y2 and dz2 orbitals point directly at the ligands. For tetrahedral complexes, the d orbitals remain in place, but with only four ligands located between the axes. None of the orbitals points directly at the tetrahedral ligands. However, the dx2−y2 and dz2 orbitals (along the Cartesian axes) overlap with the ligands less than the dxy,...