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Updated: Jan 31, 2026
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Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
Published on: May 10, 2022
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Fatal Iron Toxicity in an Adult: Clinical Profile and Review
Mandar Ramachandra Sane1, Kamal Malukani2, Rashmi Kulkarni3
1Department of Forensic Medicine and Toxicology, Government Medical College and Hospital, Chandigarh, India.
Summary
Acute iron toxicity from intentional overdose in adults is rare. This case highlights delayed treatment and fulminant hepatic failure, emphasizing the need for prompt diagnosis and management of iron poisoning.
Area of Science:
- Toxicology
- Hepatology
- Emergency Medicine
Background:
- Acute iron toxicity is commonly observed in children due to accidental ingestion of iron supplements.
- Literature regarding acute iron toxicity with suicidal intent in adults is limited.
Observation:
- An adult intentionally ingested multiple iron tablets, leading to a critical overdose.
- Delayed diagnosis of iron poisoning occurred due to initial misdiagnosis of the intoxicating agent.
Findings:
- The patient developed fulminant hepatic failure and rapid clinical deterioration following iron overdose.
- Despite intensive supportive care, the patient did not survive the toxic effects of iron.
Implications:
- This case underscores the importance of considering iron overdose in adult suicide attempts.
- Prompt recognition and management are crucial for improving outcomes in severe iron toxicity.
- Further research into adult iron poisoning is warranted to inform clinical practice.
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