Related Experiment Video

Updated: Jan 31, 2026

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
08:28

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus

Published on: April 5, 2011

18.2K

Risk Factors of Febrile Status Epilepticus

Reza Sharafi1, Afagh Hassanzadeh Rad1, Vahid Aminzadeh1

  • 1Pediatric Growth Disorder Research Center, 17 Shahrivar HospitalSchool, of Medicine , Rasht, Iran.

Iranian Journal of Child Neurology
|January 2, 2019
PubMed

Insights

Febrile status epilepticus (FSE) in children is linked to lower body temperature, younger age, and a family history of seizures or epilepsy. Premature birth also increases the risk of FSE.

Area of Science:

  • Pediatric Neurology
  • Epileptology

Background:

  • Febrile seizures (FS) are common in children, but febrile status epilepticus (FSE) represents a more severe form.
  • Identifying risk factors for FSE is crucial for early intervention and improved outcomes.

Purpose of the Study:

  • To investigate the risk factors associated with febrile status epilepticus (FSE) in children.
  • To differentiate risk factors between FSE, complex febrile seizure (CFS), and simple febrile seizure (SFS).

Main Methods:

  • A case-control study analyzed records of 756 children with first febrile seizure (FS) from 2007-2014.
  • Data collected included age, sex, feeding history, temperature, fever-to-seizure interval, family history of epilepsy/FS, and prematurity.
  • Statistical analysis used Chi-square tests to compare FSE cases with complex and simple FS controls.

Main Results:

  • Most patients (57.8%) had seizures with low-grade fever (<39 °C).
  • Lower age, lower body temperature during seizure, family history of FS/epilepsy, and premature birth were significantly associated with FSE.
  • These factors also showed significant associations when comparing FSE with complex febrile seizures.

Conclusions:

  • Key risk factors for FSE in children include lower body temperature, younger age, and a family history of febrile seizures or epilepsy.
  • Premature birth is also identified as a significant risk factor for FSE.
  • These findings emphasize the importance of considering these factors in managing children with febrile seizures.
Abstract

Keywords:
ChildrenFebrile status epilepticusRisk factor

More Related Videos

In Vitro Rearing of Solitary Bees: A Tool for Assessing Larval Risk Factors08:50

In Vitro Rearing of Solitary Bees: A Tool for Assessing Larval Risk Factors

Published on: July 16, 2018

8.7K
Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies10:11

Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies

Published on: October 22, 2014

19.7K

Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.5K
Relative Risk01:12

Relative Risk

Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
2.1K
Marcia's Theory of Identity Status01:26

Marcia's Theory of Identity Status

James Marcia's identity status model provides a framework for understanding how adolescents navigate identity formation through varying degrees of exploration and commitment. Marcia's model builds on Erik Erikson's theories of psychosocial development, focusing specifically on how adolescents reconcile individual aspirations with societal expectations. His model describes identity formation as a dynamic process where adolescents move between different states depending on their level...
1.6K
Transcription Factors02:16

Transcription Factors

Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
82.7K
Factors Affecting Solubility04:01

Factors Affecting Solubility

Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Chȃtelier’s principle. Consider the dissolution of silver iodide:
37.1K
Transcription Elongation Factors02:35

Transcription Elongation Factors

Transcription elongation is a dynamic process that alters depending upon the sequence heterogeneity of the DNA being transcribed. Hence, it is not surprising that the elongation complex's composition also varies along the way while transcribing a gene.
The transcription elongation is regulated via pausing of RNA polymerase on several occasions during transcription. In bacteria, these halts are necessary because the transcription of DNA into mRNA is coupled to the translation of that mRNA...
13.9K