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Predictors of PrEP Uptake Among Patients with Equivalent Access
Sarit A Golub1,2, Rachel A Fikslin3, Matthew H Goldberg3
1Department of Psychology, Hunter College of the City University of New York, 695 Park Avenue, New York, NY, 10065, USA. sgolub@hunter.cuny.edu.
AIDS and Behavior
|January 3, 2019
Summary
Understanding factors influencing PrEP uptake is key. Psychological variables like self-efficacy and stigma beliefs, alongside HIV risk perception and partner status, significantly impact decisions about pre-exposure prophylaxis (PrEP).
Area of Science:
- Public Health
- Behavioral Science
- Infectious Disease Prevention
Background:
- Increasing adoption of pre-exposure prophylaxis (PrEP) is crucial for HIV prevention.
- Limited research exists on individual-level factors influencing PrEP uptake, particularly those amenable to intervention.
Purpose of the Study:
- To examine behavioral and psychosocial factors differentiating patients who accepted or declined PrEP.
- To identify individual-level determinants of PrEP adoption for targeted interventions.
Main Methods:
- Analysis of data from a PrEP demonstration project at a community health center.
- Multivariable modeling to assess factors associated with PrEP acceptance versus decline.
Main Results:
- Higher odds of PrEP acceptance were linked to having an HIV-positive partner, increased recent risk behavior, and greater HIV risk perception.
- PrEP adoption correlated positively with adherence self-efficacy and negatively with perceived sensitivity to medicines.
- Psychological factors, including stigma and medication beliefs, were associated with PrEP uptake, independent of demographics and socioeconomic status.
Conclusions:
- PrEP uptake decisions are influenced by objective/subjective HIV risk, psychological variables (stigma, medication beliefs), and self-efficacy.
- These findings highlight opportunities for educational and behavioral interventions to enhance PrEP adoption.
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