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Related Experiment Videos

[Cellular homeostasis and trace elements].

A P Avtsyn, L S Strochkova, A A Zhavoronkov

    Arkhiv Patologii
    |January 1, 1988
    PubMed
    Summary
    This summary is machine-generated.

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    [Prion disease and brain amyloidosis].

    Arkhiv patologii·1999

    Essential and toxic elements impact cellular homeostasis, with varying cellular uptake and release pathways. Some trace elements are linked to cancer, while others offer protection.

    Area of Science:

    • Cell Biology
    • Toxicology
    • Biochemistry

    Context:

    • Cellular homeostasis is crucial for organismal health.
    • Essential and toxic elements play dual roles in biological systems.
    • Understanding element transport and accumulation is key to cellular function.

    Purpose:

    • To review the role of essential and toxic elements in cellular homeostasis.
    • To explore the pathways of element introduction and release in cells.
    • To examine the relationship between trace elements, cell morphology, and disease.

    Summary:

    • This study examines how essential and toxic elements affect cellular homeostasis, including their entry/exit routes, ligand interactions, and intracellular distribution.
    • Morphological data on trace element accumulation in cells, organs, and cellular compartments are presented.

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  • The research highlights that certain trace elements can induce mutagenesis and carcinogenesis, whereas others exhibit anticarcinogenic and antiblastic effects.

    • Impact:

    • Provides insights into the mechanisms of element-induced cellular dysfunction and protection.
    • Highlights the complex role of trace elements in health and disease.
    • Informs potential therapeutic strategies involving trace element modulation.