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Updated: Jan 31, 2026

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Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
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Loneliness in Multiple Sclerosis: Possible Antecedents and Correlates
Julia M Balto1, Lara A Pilutti1, Robert W Motl1
1Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Summary
Individuals with multiple sclerosis (MS) experience higher loneliness than healthy adults. This is linked to factors like marital status, disability, depression, and fatigue.
Area of Science:
- Neurology
- Psychology
- Social Science
Background:
- Multiple sclerosis (MS) is a chronic neurological condition affecting millions worldwide.
- Loneliness is a significant psychosocial concern that can impact overall well-being.
Purpose of the Study:
- To investigate the prevalence of loneliness in individuals with multiple sclerosis (MS).
- To identify potential antecedents and correlates of loneliness in the MS population.
Main Methods:
- A cross-sectional, comparative study design was employed.
- Data were collected from 63 individuals with MS and 21 healthy adults using self-report measures.
- Inferential statistics were used to analyze the data.
Main Results:
- Individuals with MS reported significantly higher loneliness scores compared to healthy adults.
- Employment status, marital status, and various disability measures (social and personal limitations) were associated with loneliness.
- Depression, cognitive and psychosocial fatigue, and psychological quality of life were identified as significant correlates of loneliness.
Conclusions:
- Loneliness is a prevalent issue in individuals diagnosed with multiple sclerosis (MS).
- Marital status, disability limitations, depression, and fatigue are key factors associated with loneliness in MS.
- Clinicians should recognize and address loneliness as an important aspect of MS care.
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