Related Experiment Video
Updated: Jan 31, 2026

An Anatomical Study of Nerves at Risk During Minimally Invasive Hallux Valgus Surgery
Published on: February 17, 2018
Increased Risk for Invasive Group A Streptococcus Disease for Household Contacts of Scarlet Fever Cases, England,
Scarlet fever is at a 50-year high. Household contacts of scarlet fever cases have a 12.2-fold increased risk of invasive group A Streptococcus (iGAS) disease, particularly infants and the elderly.
Area of Science:
- Infectious Diseases
- Epidemiology
- Public Health
Background:
- Scarlet fever incidence in England and Wales reached a 50-year peak between 2011-2016.
- Invasive group A Streptococcus (iGAS) disease is a serious complication requiring prompt recognition.
Observation:
- A study analyzed secondary household risk for iGAS disease following scarlet fever.
- Data from 2011-2016 linked scarlet fever reports to laboratory-confirmed iGAS infections in household contacts.
Findings:
- Eleven iGAS cases were identified among approximately 189,684 household contacts.
- The 60-day iGAS incidence rate in contacts was 35.3 cases/100,000 person-years, 12.2 times higher than the background rate.
- Infants and individuals over 75 years old faced the highest risk; three cases were fatal, with sepsis and cellulitis being common.
- Emm typing revealed emm 1.0 as the predominant strain (n=4).
Implications:
- While the absolute risk is low, heightened awareness among clinicians is crucial for timely diagnosis and treatment of iGAS in household contacts.
- This underscores the importance of monitoring scarlet fever trends and associated iGAS risks.
- Early intervention can significantly improve outcomes for invasive group A Streptococcus infections.
More Related Videos
11:16Non-invasive Imaging of the Innate Immune Response in a Zebrafish Larval Model of Streptococcus iniae Infection
Published on: April 21, 2015
10:11Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies
Published on: October 22, 2014
Related Concept Videos
Types of Fever
Here are the different types of fever:
Patterns of Fever
Household Wiring And Electrical Safety
Methods of reducing fever
Pharmacological Methods of Reducing Fever:
Contact Angle
The adhesive force is the molecular force between molecules of different materials, that is, between the molecules of the solid and the liquid. The cohesive...
Contact-dependent Signaling
Gap Junctions
In animal cells, gap junctions are formed...