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Estimating the Yield of Compounds on the TLC Plate via the Blue-LED Illumination Technique
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Transscleral LED illumination pen.

Christian Lingenfelder1, Frank Koch2, Philipp Koelbl3

  • 1Pharmpur GmbH, Messerschmittring 33, 86343 Koenigsbrunn, Germany.

Biomedical Engineering Letters
|January 4, 2019
PubMed
Summary
This summary is machine-generated.

A novel pen-like device uses a white LED to provide safe intraocular illumination through the sclera, avoiding incisions and retinal damage. This simple, gentle, and cost-effective tool offers sufficient light for surgical and diagnostic needs.

Keywords:
Photochemical hazardRetinal diagnosticsThermal hazardTransscleral illuminationWhite LED

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Medical Devices

Background:

  • Traditional intraocular illumination devices are bulky, expensive, and pose risks like photochemical retinal damage due to invasive light guide insertion.
  • Current methods necessitate incisions, increasing infection risk and patient discomfort.

Purpose of the Study:

  • To develop and evaluate a novel, safe, and simple device for intraocular illumination.
  • To assess the thermal and photochemical risks associated with the new illumination method.

Main Methods:

  • A white light-emitting diode (LED) integrated into a pen-like holder was developed.
  • The device was designed to be pressed against the sclera, transmitting light transsclerally without incisions.
  • Thermal and photochemical safety assessments were conducted, referencing relevant medical device standards.

Main Results:

  • The transscleral illumination device demonstrated sufficient intraocular light levels for surgical and diagnostic applications.
  • Safety evaluations confirmed the device poses no harm to the patient, meeting relevant standards.
  • Testing on the authors' eyes validated the device's efficacy and safety.

Conclusions:

  • The developed pen-like LED device offers a safe, simple, and gentle alternative for intraocular illumination.
  • It eliminates the risks associated with invasive light guides and incisions.
  • This innovation provides a cost-effective and patient-friendly solution for ophthalmic procedures.