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Cadherins in Tissue Organization01:19

Cadherins in Tissue Organization

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The cadherins are a superfamily of cell adhesion molecules comprising over 180 variants, with specific tissues expressing a particular combination of cadherin types. Cadherins generally exhibit homophilic binding; i.e., cadherins on one cell bind to cadherins of the same or closely related type on another cell. Thus, cells of the same type have a specific affinity to bind to each other and sort themselves into clusters to form tissues.
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Related Experiment Video

Updated: Jan 31, 2026

Human Cartilage Tissue Fabrication Using Three-dimensional Inkjet Printing Technology
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Current advances in three-dimensional tissue/organ printing.

Jeong Hun Park1, Jinah Jang1, Jung-Seob Lee1

  • 11Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, Korea.

Tissue Engineering and Regenerative Medicine
|January 4, 2019
PubMed
Summary

Three-dimensional (3D) tissue printing advances regenerative medicine by creating living tissue analogues. Innovations in bio-inks and printing techniques enhance the functionality of these 3D constructs for future applications.

Keywords:
3D tissue/organ analogue3D tissue/organ printingBio-inkIn vitro tissue modelTissue engineering and regenerative medicine

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Area of Science:

  • Tissue Engineering
  • Regenerative Medicine
  • Bioprinting

Background:

  • Three-dimensional (3D) tissue/organ printing is a key innovation in tissue engineering and regenerative medicine.
  • This technology aims to fabricate 3D living tissue/organ analogues using computer-aided 3D printing techniques.

Purpose of the Study:

  • To provide an overview of current 3D tissue/organ printing techniques and biomaterials.
  • To discuss the development of 3D tissue/organ analogues and in vitro models.
  • To identify future perspectives in the field of 3D tissue/organ printing.

Main Methods:

  • Application of computer-aided 3D printing techniques.
  • Utilizing printable biomaterials, including decellularized extracellular matrix bio-inks.
  • Development of 3D tissue/organ analogues and in vitro models.

Main Results:

  • Advancements in 3D printing techniques have enabled precise deposition of cells and biomaterials.
  • Novel biomaterials, such as decellularized extracellular matrix bio-inks, improve the functionality of 3D tissue analogues.
  • Development of sophisticated in vitro models for tissue engineering applications.

Conclusions:

  • 3D tissue/organ printing holds significant promise for regenerative medicine.
  • Continued innovation in printing techniques and biomaterials is crucial for advancing the field.
  • Future research should focus on enhancing the complexity and functionality of engineered tissues and organs.