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Updated: Jan 31, 2026

Encapsulation of Cardiomyocytes in a Fibrin Hydrogel for Cardiac Tissue Engineering
Published on: September 19, 2011
Biopolymeric In Situ Hydrogels for Tissue Engineering and Bioimaging Applications
Adonijah Graham Sontyana1, Ansuja Pulickal Mathew1, Ki-Hyun Cho2
11Department of Biomedical Sciences, Chonnam National University, Chonnam National University Medical School, 160 Baekseo-ro, Dong-gu, Gwangju, 61469 Republic of Korea.
Background:
Biopolymeric in situ hydrogels play a crucial role in the regenerative repair and replacement of infected or injured tissue. They possess excellent biodegradability and biocompatibility in the biological system, however only a few biopolymeric in situ hydrogels have been approved clinically. Researchers have been investigating new advancements and designs to restore tissue functions and structure, and these studies involve a composite of biometrics, cells and a combination of factors that can repair or regenerate damaged tissue.
Methods:
Injectable hydrogels, cross-linking mechanisms, bioactive materials for injectable hydrogels, clinically applied injectable biopolymeric hydrogels and the bioimaging applications of hydrogels were reviewed.
Results:
This article reviews the different types of biopolymeric injectable hydrogels, their gelation mechanisms, tissue engineering, clinical applications and their various in situ imaging techniques.
Conclusion:
The applications of bioactive injectable hydrogels and their bioimaging are a promising area in tissue engineering and regenerative medicine. There is a high demand for injectable hydrogels for in situ imaging.
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