Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Formation of Muscle Fibers from Myoblasts01:13

Formation of Muscle Fibers from Myoblasts

6.0K
De novo myogenesis, or the formation of muscle fibers, begins during the early embryonic stages. The skeletal muscle is formed from somites– blocks of embryonic cell layers. The somites are further divided into dermatomes, myotomes, sclerotomes, and syndetomes. Among these, the myotomes give rise to muscle fibers.
Muscle progenitor cells (MPCs) are formed from the myotomes. MPCs express genes that encode the transcription factors Pax3 and Pax7. Along with Pax 3/7, other transcription...
6.0K
Ionic Crystal Structures02:42

Ionic Crystal Structures

17.0K
Ionic crystals consist of two or more different kinds of ions that usually have different sizes. The packing of these ions into a crystal structure is more complex than the packing of metal atoms that are the same size.
Most monatomic ions behave as charged spheres, and their attraction for ions of opposite charge is the same in every direction. Consequently, stable structures for ionic compounds result (1) when ions of one charge are surrounded by as many ions as possible of the opposite...
17.0K
Crystal Growth: Principles of Crystallization01:25

Crystal Growth: Principles of Crystallization

5.0K
Crystallization is a phase transformation process in which crystals are precipitated from a supersaturated solution or formed from other sources. During crystallization, atoms or molecules arrange themselves into a well-defined, rigid crystal lattice to minimize energy.
Initiating crystallization involves manipulating the concentration of the solute and the temperature of the solution. Since crystal growth occurs when the ratio of concentration and solubility of the solute in the solvent...
5.0K
Crystal Field Theory - Octahedral Complexes02:58

Crystal Field Theory - Octahedral Complexes

30.8K
Crystal Field Theory
To explain the observed behavior of transition metal complexes (such as colors), a model involving electrostatic interactions between the electrons from the ligands and the electrons in the unhybridized d orbitals of the central metal atom has been developed. This electrostatic model is crystal field theory (CFT). It helps to understand, interpret, and predict the colors, magnetic behavior, and some structures of coordination compounds of transition metals.
CFT focuses on...
30.8K
Design Example: Alignment of a Road Line Using GIS01:17

Design Example: Alignment of a Road Line Using GIS

350
The alignment of a road line using Geographic Information Systems (GIS) is a critical process in civil engineering, combining advanced technology with practical decision-making. This methodology begins with the collection of geospatial data, including information on land cover, geomorphology, drainage patterns, slope, and contour details. Such data is typically acquired through satellite imagery and GIS tools, offering a comprehensive understanding of the terrain.Once the data is gathered, it...
350
Crystal Field Theory - Tetrahedral and Square Planar Complexes02:46

Crystal Field Theory - Tetrahedral and Square Planar Complexes

48.4K
Tetrahedral Complexes
Crystal field theory (CFT) is applicable to molecules in geometries other than octahedral. In octahedral complexes, the lobes of the dx2−y2 and dz2 orbitals point directly at the ligands. For tetrahedral complexes, the d orbitals remain in place, but with only four ligands located between the axes. None of the orbitals points directly at the tetrahedral ligands. However, the dx2−y2 and dz2 orbitals (along the Cartesian axes) overlap with the ligands less than the dxy,...
48.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Levoglucosenone-Derived Isothiocyanates as Antifungal Compounds: Merging Sustainability and Medicinal Chemistry.

ChemMedChem·2026
Same author

Polydomain Liquid Crystal Elastomers with Mechanically Switchable Opacity for Thermal Shielding.

ACS polymers Au·2026
Same author

Boosting Ferroelectricity: 2D and Polymer Ferroelectric Hybrids Enabling Ambipolar Nonvolatile MoS<sub>2</sub> Memory Transistor.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Multivalent C2-alkyl trihydroxypiperidine architectures modulate β-glucocerebrosidase activity.

European journal of medicinal chemistry·2026
Same author

Programmable ion-protein networks from sodium caseinate: a sustainable platform for soft functional materials.

Materials horizons·2026
Same author

Engineering oxaliplatin(IV) prodrugs with monohaloacetates for redox-responsive and multimodal anticancer activity.

Dalton transactions (Cambridge, England : 2003)·2026
Same journal

Oxygen-Independent Supramolecular Nanoplatform for Photothermal-Thermodynamic Therapy against Periodontal Anaerobic Infections.

Advanced healthcare materials·2026
Same journal

An All-in-One Nanoplatform for Synergistic Anti-Infection and Healing of Diabetic Wounds via Photothermal-Gas Therapy.

Advanced healthcare materials·2026
Same journal

Bioactive Hydrogels with D-Amino Acid RGD Mimics: A Therapeutic Strategy for Expeditious Infected Wound Closure.

Advanced healthcare materials·2026
Same journal

An Asymmetric Dura-Inspired Collagen Hydrogel Patch with Integrated Dense-Porous Architecture Enabled by Dual-Channel Freeze Casting.

Advanced healthcare materials·2026
Same journal

Pathology-Targeted Nanoparticles Guided by Peptide Remodel the Periodontal Microenvironment for Periodontitis Therapy.

Advanced healthcare materials·2026
Same journal

Gellan Gum Fluid Gel System for Controlled-Delivery of Cytokine-Licensed MSC-EVs to Enhance Corneal Repair in Limbal Stem Cell Deficiency.

Advanced healthcare materials·2026
See all related articles

Related Experiment Video

Updated: Jan 31, 2026

Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures
13:38

Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures

Published on: April 11, 2017

10.1K

Liquid Crystal-Induced Myoblast Alignment.

Daniele Martella1,2,3, Lorenzo Pattelli2,4,5, Camilla Matassini1,3

  • 1Department of Chemistry "Ugo Schiff", University of Florence, via della Lastruccia 3-13, 50019, Sesto Fiorentino, Italy.

Advanced Healthcare Materials
|January 4, 2019
PubMed
Summary
This summary is machine-generated.

Researchers developed a new method for controlling cell alignment using liquid crystalline networks. This technique shows promise for tissue engineering and creating biohybrid materials by guiding cell organization on polymeric scaffolds.

Keywords:
biomaterialscell alignmentliquid crystalline alignmentsliquid crystalline networkmuscular tissue engineering

More Related Videos

Preparation of Monodomain Liquid Crystal Elastomers and Liquid Crystal Elastomer Nanocomposites
12:21

Preparation of Monodomain Liquid Crystal Elastomers and Liquid Crystal Elastomer Nanocomposites

Published on: February 6, 2016

13.5K
High-Contrast and Fast Photorheological Switching of a Twist-Bend Nematic Liquid Crystal
06:24

High-Contrast and Fast Photorheological Switching of a Twist-Bend Nematic Liquid Crystal

Published on: October 31, 2019

6.9K

Related Experiment Videos

Last Updated: Jan 31, 2026

Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures
13:38

Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures

Published on: April 11, 2017

10.1K
Preparation of Monodomain Liquid Crystal Elastomers and Liquid Crystal Elastomer Nanocomposites
12:21

Preparation of Monodomain Liquid Crystal Elastomers and Liquid Crystal Elastomer Nanocomposites

Published on: February 6, 2016

13.5K
High-Contrast and Fast Photorheological Switching of a Twist-Bend Nematic Liquid Crystal
06:24

High-Contrast and Fast Photorheological Switching of a Twist-Bend Nematic Liquid Crystal

Published on: October 31, 2019

6.9K

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Polymer Science

Background:

  • Controlling cell alignment is crucial for in vitro tissue development and creating functional biohybrid materials.
  • Standard cell culture supports lack precise control over cell organization morphology.
  • Techniques like patterned or stimulated substrates are used to induce cellular alignment.

Purpose of the Study:

  • To present a novel approach for in vitro muscular tissue morphogenesis using liquid crystalline networks.
  • To investigate the influence of liquid crystalline networks on myoblast cell alignment.

Main Methods:

  • Utilizing smooth polymeric films with planar homogeneous alignment.
  • Culturing myoblasts on these aligned polymeric films.
  • Comparing cell organization on different sample types (nematic, homeotropic, isotropic).

Main Results:

  • A degree of cellular order was observed in myoblast cultures on aligned polymeric films.
  • The direction of higher cell alignment corresponded to the nematic director of the polymer.
  • No significant cell organization was observed on homeotropic or isotropic samples.

Conclusions:

  • This study demonstrates the first instance of cellular alignment induced by interaction with a nematic polymeric scaffold.
  • Liquid crystal polymers can act as active matter to control tissue growth.
  • This approach opens new avenues for applications in tissue engineering and biohybrid materials.