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    Area of Science:

    • Veterinary Medicine
    • Infectious Diseases
    • Public Health

    Background:

    • Rabies remains a significant public health concern, particularly in developing countries.
    • International travel increases the risk of exposure to zoonotic diseases like rabies.

    Observation:

    • A patient in Virginia was diagnosed with rabies after a dog bite sustained in India.
    • The rabies virus strain was confirmed to be circulating in dogs in India.

    Findings:

    • Despite medical intervention, the patient succumbed to the illness, marking the ninth rabies death in the U.S. since 2008 among individuals exposed abroad.
    • Postexposure prophylaxis (PEP) was recommended for 72 healthcare workers (29%) who assessed exposure to the patient, incurring substantial pharmaceutical costs.

    Implications:

    • International travelers, especially those visiting rabies-endemic regions for extended periods or engaging in high-risk activities, should seek pretravel consultations.
    • Rabies preexposure vaccination is a critical preventive measure for at-risk travelers to mitigate the potentially fatal consequences of rabies exposure.