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Updated: Jan 31, 2026

Synthesis and Functionalization of Nitrogen-doped Carbon Nanotube Cups with Gold Nanoparticles as Cork Stoppers
Published on: May 13, 2013
Nitrogen-doped carbon dots rapid and selective detection of mercury ion and biothiol and construction of an
Sen Liao1, Xinzong Li1, Hua Yang1
1College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, Hunan, China.
Abstract:
Nitrogen-doped carbon dots (N-CDs) were prepared by adjusting the ratio of carbon sources (citric acid) and nitrogen sources (ethanolamine). This N-CDs fluorescent probe had been successfully applied to rapidly, sensitively and selectively determine the concentration of mercury ion (Hg2+) with a linear range of 0.1-5.0 μM and a limit of detection of 0.019 μM. In this work, it was demonstrated that N-CDs show the fluorescence response toward Hg2+ when the carboxyl groups of citric acid reacts completely with the amino groups of ethanolamine. In addition, the quenched N-CDs/Hg2+ system could be recovered by biothiol, such as cysteine (Cys), homocysteine (Hcy) and glutathione (GSH), exhibiting a sensitive response toward Cys and Hcy over GSH in HEPES buffer. N-CDs could be used as a potential fluorescent bioimaging material due to their low toxicity and good biocompatibility. Furthermore, an IMPLICATION logic gate based on Hg2+ and biothiol was constructed.
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