Related Experiment Video
Updated: Jan 31, 2026

Lower Limb Biomechanical Analysis of Healthy Participants
Published on: April 15, 2020
A comprehensive biomechanical analysis of sacral alar iliac fixation: an in vitro human cadaveric model
Bryan W Cunningham1, Paul D Sponseller2, Ashley A Murgatroyd1
11MedStar Musculoskeletal Education and Research Institute, Department of Orthopaedic Surgery, MedStar Union Memorial Hospital.
Abstract:
In BriefIn this in vitro investigation, we compared the multidirectional flexibility properties of sacral alar iliac fixation with conventional methods of sacral and sacroiliac fixation using nondestructive and destructive investigative methods. The study demonstrated that S1-2 sacral fixation alone significantly increases sacroiliac motion under all loading modalities, while sacral alar iliac fixation reduced motion in axial rotation at the sacroiliac joint and offers potential advantages of a lower instrumentation profile and ease of assembly compared to conventional sacroiliac screw instrumentation.
Related Concept Videos
Fixation and Sectioning
The simplest type of preparation is the wet mount, in which the specimen is placed in a drop of liquid on the slide. A liquid specimen can be directly deposited on the slide using a dropper. Solid specimens, such as skin scraping, can be placed on the slide before adding a drop of liquid to prepare the wet mount. Sometimes the liquid is simply water, but stains are often added...
Carbon-dioxide Fixation
Mechanistic Models: Compartment Models in Individual and Population Analysis
In Vitro Drug Dissolution: Compendial Testing Models I
In Vitro Drug Dissolution: Compendial Testing Models II
Analysis Methods of Pharmacokinetic Data: Model and Model-Independent Approaches
The model approach uses mathematical models to describe changes in drug concentration over time. Pharmacokinetic models help characterize drug behavior in patients, predict drug concentration in the body fluids, calculate optimum dosage regimens, and evaluate the risk of toxicity. However, ensuring that the model fits the experimental data accurately...

