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Updated: Jan 31, 2026

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
Published on: May 2, 2025
A Novel Method for Fracture Blister Management Using Circumferential Negative Pressure Wound Therapy with
Ian G Hasegawa1, John P Livingstone2, Patrick Murray2
1Orthopedic Surgery, University of Hawaii, John A. Burns School of Medicine, Honolulu, USA.
Abstract:
High- and low-energy fractures can result in nearby skin blistering. These so-called "fracture blisters" can be troublesome in the face of surgery and currently no uniform consensus regarding their management exists. Preoperatively, we used circumferential negative pressure wound therapy with sterile saline instillation (NPWT-id) to treat two patients with closed fractures who had developed significant skin blistering. This technique resulted in near complete re-epithelialization of the decompressed blister beds within one week. Furthermore, no excessive surgical delay or alteration in surgical approach was necessary, and both patients healed successfully without post-operative wound complications. Thus, circumferential NPWT-id may be a worthwhile treatment option for fracture blisters.
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