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A Review on Bioengineering Approaches to Insulin Delivery: A Pharmaceutical and Engineering Perspective
Zahra Baghban Taraghdari1, Rana Imani1, Fatemeh Mohabatpour1,2
1Z. Baghban Taraghdari, Dr. R. Imani, F. Mohabatpour, Department of Biomedical Engineering, Amirkabir University of Technology, Tehran, 15875/4413, Iran.
Abstract:
Diabetes mellitus (DM) is the most prevalent non-contagious disease, which has affected a large number of people all over the world. Among all treatments known to have a positive influence in the control of DM, insulin therapy is the most common and effective one. Nowadays, various methods of insulin delivery are under investigation, which are able to reach a plausible bioavailability with ignorable side effects instead of insulin injection. This article presents a comprehensive review of the insulin therapy approach with a focus on modified methods in insulin delivery strategies and current advances in engineered insulin delivery systems.
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