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Updated: Jan 31, 2026

A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes
Published on: September 15, 2018
Early diagnosis and treatment of familial hypercholesterolemia
1J. Casey Elkins is an assistant professor, director of the DNP program, and clinical lipidology coordinator at the University of South Alabama, Mobile, Ala. Sharon Fruh is a professor and associate dean of research, evaluation, and development at the University of South Alabama, Mobile, Ala.
Abstract:
If undiagnosed and untreated, familial hypercholesterolemia can lead to serious cardiac complications, such as premature atherosclerotic cardiovascular disease. NPs should be familiar with the clinical presentation of this inherited metabolic disease to diagnose patients as early as possible and promptly begin treatment that may include lifestyle changes, statin therapy, and/or nonstatin therapy.
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