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[Is there interrelationship between percentage of hemolysis and clots in samples of venous blood?]

A V Moshkin, M L Sveschinsky, N A Steriopolo

    Klinicheskaia Laboratornaia Diagnostika
    |January 8, 2019
    PubMed

    The most failures in the process of laboratory analysis occur at the pre-analytical stage. The percentage of samples of blood serum with hemolysis and percentage of samples of EDTA of whole blood with clots are largely applied as indices of quality of venous blood sampling. The analysis of data from 28 laboratories established no relationship between percentage ofsamples with hemolysis and percentage of samples with clots. Prior to implementation of more large-scaled studies, the level less than 1% of samples with hemolysis can be accepted as a minimal level of quality of blood sampling and the level less than 0.4% of samples of total blood with clots can be accepted as a minimal level of quality ofpreparation of samples after blood drawing from vein for analysis using hematological analyzers. both indices can be applied for estimating efficiency of measures concerning amelioration of quality of procedure of blood drawing from vein. By all appearances, the ideal sample for control of quality of blood drawing in the nearest future can become sample of blood drew from vein into vial with citrate for analysis using modern coagulometric analyzer. This sample can become a source for calculation of several indices of quality of venous blood drawing (hemolysis, clots, vial filling and violation of ration sample-anticoagulant).

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