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Updated: Jan 31, 2026

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
Published on: April 22, 2015
Toddler Screening for Autism Spectrum Disorder: A Meta-Analysis of Diagnostic Accuracy
Ana B Sánchez-García1, Purificación Galindo-Villardón2, Ana B Nieto-Librero2
1INICO-University of Salamanca, Pso. Canalejas, 169, 37008, Salamanca, Spain. asg@usal.es.
Abstract:
Great efforts focus on early detection of autism spectrum disorder, although some scientists and policy-makers have questioned early universal screening. The aim of this meta-analysis was to evaluate the diagnostic accuracy of the different screening tools. Several electronic databases were used to identify published studies. A Bayesian model was used to estimate the screening accuracy. The pooled sensitivity was 0.72 (95% CI 0.61-0.81), and the specificity was 0.98 (95% CI 0.97-0.99). Subgroup analyses to remove heterogeneity indicated sensitivity was 0.77 (95% CI 0.69-0.84), and specificity was 0.99 (95% CI 0.97-0.99; SD ≤ 0.01). Level 1 screening tools for ASD showed consistent statistically significant results and therefore are adequate to detect autism at 14-36 months.
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