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Murine Model of Epicutaneously-Induced Immunomodulation
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[Immunomodulators and hemopoietic system in malignant growth]

A V Sanin, M A Tumanian

    Eksperimental'Naia Onkologiia
    |January 1, 1988
    PubMed

    The data on the effect of immunomodulators (IM) of the biologic origin on hematopoietic responses are reviewed. Up-to-date classification of immunomodulators is given. The correlation between the proliferative stem cell response induced by certain immunomodulators, accidental thymus involution, suppressor T cell activity enhancement and the development of transient anemia are analyzed from the standpoint of its possible significance. A conclusion is drawn on the necessity to develop systemic criteria which permit evaluating shifts induced by immunomodulators in the hematopoietic system.

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