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Bacterial keratitis after penetrating keratoplasty
1Research Department, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Ophthalmology
|November 1, 1988
Summary
Bacterial keratitis after penetrating keratoplasty is a significant concern, especially in developing nations. Proactive patient selection and meticulous pre- and post-operative care can help prevent this serious eye infection.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Bacterial keratitis poses a substantial challenge, particularly in developing countries.
- Penetrating keratoplasty is a common surgical procedure for corneal diseases.
Purpose of the Study:
- To investigate the incidence and causative agents of bacterial keratitis following penetrating keratoplasty.
- To identify predisposing risk factors for postoperative bacterial keratitis.
Main Methods:
- A retrospective study of 881 patients (947 procedures) undergoing penetrating keratoplasty from January 1983 to March 1986.
- Clinical follow-up for at least 6 months post-surgery to monitor for complications.
- Analysis of causative bacterial organisms and statistical identification of risk factors.
Main Results:
- Bacterial keratitis developed in 11.9% of eyes post-penetrating keratoplasty.
- Common causative organisms included Streptococcus pneumoniae, Staphylococcus epidermidis, and Pseudomonas aeruginosa.
- Significant risk factors identified were trichiasis, epithelial defects, soft contact lens wear, and eroding sutures.
Conclusions:
- Postoperative bacterial keratitis following penetrating keratoplasty is a notable complication.
- Effective management strategies involve careful patient selection and comprehensive pre- and post-operative ocular condition management.
- Minimizing incidence requires addressing identified risk factors like trichiasis and epithelial defects.