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Updated: Jan 31, 2026

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
Published on: June 9, 2023
Saccharomyces-derived carbon dots for biosensing pH and vitamin B 12
Ying Yu1, Chunguang Li1, Cailing Chen1
1State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, Jilin University, Changchun 130012, People's Republic of China.
Abstract:
Photoluminescence(PL) nano-biosensors that can be used for accurately and reliably monitoring pH and vitamin hold a great promise in biology and medicine. Herein, a high quantum yield of 16% saccharomyces-derived N-doped carbon dots (s-N-CDs) was synthesized through a simple and one-pot microwave-assisted hydrothermal approach. The produced s-N-CDs are an excellent multi-functional biosensor for the applications of pH sensing and vitamin probing. Fluorescence intensity and fluorescence lifetime dramatically increases with pH decreasing from 14 to 2. Moreover, the fluorescence intensity presents highly reversible abilty from 13 to 2 without any profound attenuation after ten consecutive circles. More importantly, the CDs prepared herein are sound option for assaying cobalamin (VB 12) based fluorescence resonance energy transfer (FRET) with a superior low detection limit of 2.19 μM.
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The Dot Product
Dot Product
In engineering, the dot product of any two vectors is the product of the magnitudes of the vectors and the cosine of the angle between them. It is denoted by a dot symbol between the two vectors.
Consider a vehicle pulling an object along the ground using a rope. If the rope makes an angle with the horizontal axis, the work done can be calculated using the dot product of the force applied and the object's displacement.
The dot...
Dot Product: Problem Solving
Identify the problem: Start by reading the problem and...