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Intracranial Hemorrhaging Following Cardiobacterium hominis Endocarditis

Eitaro Okumura1, Junya Tsurukiri1, Hiroshi Yamanaka2

  • 1Emergency and Critical Care Medicine, Tokyo Medical University Hachioji Medical Center, Japan.

Internal Medicine (Tokyo, Japan)
|January 11, 2019
PubMed

Insights

Infectious endocarditis (IE) can cause deadly intracranial hemorrhaging (ICH). This case highlights Cardiobacterium hominis as a rare IE cause of ICH, emphasizing the need for vigilant diagnosis and treatment.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Neurology

Background:

  • Infectious endocarditis (IE) is a severe infection with high mortality, often linked to intracranial hemorrhaging (ICH).
  • Staphylococcus aureus is the most frequent pathogen in IE cases.
  • The association between IE and ICH necessitates prompt diagnosis and management.

Observation:

  • This report details a rare case of subacute IE caused by Cardiobacterium hominis.
  • The patient presented with intracranial hemorrhaging (ICH) secondary to the infection.
  • Literature review identified only seven prior cases of IE caused by Cardiobacterium hominis leading to ICH.

Findings:

  • Cardiobacterium hominis is an uncommon but significant cause of IE-associated ICH.
  • This case expands the known spectrum of IE pathogens linked to severe neurological complications.
  • The rarity of this specific pathogen-induced ICH underscores diagnostic challenges.

Implications:

  • Prolonged, culture-specific antibiotic therapy is crucial for treating IE caused by unusual organisms like Cardiobacterium hominis.
  • Extended blood culture surveillance is essential for timely detection and intervention in complex IE cases.
  • Increased awareness of rare pathogens in IE is vital for improving patient outcomes and preventing neurological sequelae.

Keywords:
HACEKblood cultureinfectious endocarditisstrokevalvular disease

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