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Updated: Jan 31, 2026

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Inducement and Evaluation of a Murine Model of Experimental Myopia
Published on: January 22, 2019
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Bilateral Angle Narrowing and Acute Myopia Induced by Indapamide: A Case Report
Ana Catarina Pedrosa1, Joana Rodrigues Araújo1, João Paulo Macedo1
1Department of Ophthalmology, Centro Hospitalar São João, Porto, Portugal.
Case Reports in Ophthalmological Medicine
|January 11, 2019
Summary
Indapamide medication can cause acute myopia and angle closure due to ciliochoroidal effusion. Prompt diagnosis and drug withdrawal lead to full recovery without lasting effects.
Area of Science:
- Ophthalmology
- Pharmacology
Background:
- Diuretic medications are commonly prescribed for hypertension.
- Sulfonamide-derived drugs, including indapamide, can have ocular side effects.
Observation:
- A case report details a 37-year-old man experiencing acute bilateral blurry vision after starting indapamide and amlodipine.
- Clinical examination revealed myopia, anterior chamber angle narrowing, and ciliochoroidal effusion.
Findings:
- Ultrasound biomicroscopy confirmed bilateral ciliochoroidal effusion and angle narrowing.
- Discontinuation of indapamide and management of intraocular pressure resulted in complete resolution of symptoms.
Implications:
- Indapamide can induce reversible acute myopia and angle closure glaucoma.
- Early recognition and withdrawal of indapamide are crucial for preventing permanent vision loss.
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