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Multimodal 3D Printing of Phantoms to Simulate Biological Tissue
Published on: January 11, 2020
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The ADAM-pelvis phantom-an anthropomorphic, deformable and multimodal phantom for MRgRT
N I Niebuhr1, W Johnen, G Echner
1Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany. National Center for Radiation Research in Oncology, Heidelberg Institute for Radiooncology, Heidelberg, Germany. Department of Physics and Astronomy, Heidelberg University, Heidelberg, Germany. Author to whom any correspondence should be addressed.
Physics in Medicine and Biology
|January 11, 2019
Summary
We developed the ADAM-pelvis phantom, a realistic male pelvis model for validating image-guided radiotherapy tools. This deformable, multimodal phantom accurately simulates organ motion and imaging artifacts, improving treatment accuracy.
Area of Science:
- Medical Physics
- Radiotherapy Technology
- Medical Imaging
Background:
- Image-guided radiotherapy (IGRT) tools require validation under realistic conditions.
- Patient-specific anatomical variations and organ motion pose challenges in IGRT.
Purpose of the Study:
- To present the construction and validation of the ADAM-pelvis phantom.
- To create an anthropomorphic, deformable, multimodal phantom for IGRT workflow assessment.
Main Methods:
- Constructed an anthropomorphic male pelvis phantom using 3D printing and silicone.
- Incorporated surrogates for tissues (muscle, adipose, bone) and deformable organs (bladder, rectum, prostate).
- Ensured multimodal imaging compatibility (CT/MRI) with accurate tissue mimicry and included markers for dosimetry.
Main Results:
- The ADAM-pelvis phantom accurately mimics CT and MRI characteristics of human tissues.
- Reproducible interfractional organ motion (bladder, rectum) was achieved with <1mm deviation.
- Simulated organ motion induced realistic prostate displacement, rotation, and deformation.
Conclusions:
- The ADAM-pelvis phantom provides a validated solution for testing IGRT workflows.
- The phantom's design and construction techniques are adaptable for other anthropomorphic phantoms.
- Enables systematic investigation of IGRT in the presence of anatomical and motion uncertainties.
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