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Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue
Published on: July 28, 2023
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Keloid Formation due to Repetitive Mammographies
Tim Pruimboom1,2, Marc R Scheltinga2
1Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.
Case Reports in Dermatology
|January 12, 2019
Summary
Repetitive mammographies can trigger abnormal wound healing, leading to symptomatic keloid formation. This case highlights a rare complication of excessive keloid growth from frequent breast imaging.
Area of Science:
- Dermatology
- Oncology
- Radiology
Background:
- Keloids are benign, fibroproliferative tumors resulting from abnormal wound healing after skin injury.
- They present as firm, hyperpigmented, and sometimes tender growths with a glossy surface.
- Repetitive trauma or chronic irritation can contribute to keloid development.
Observation:
- This case report details excessive keloid formation in a patient undergoing repetitive mammography procedures.
- The patient experienced symptomatic and cosmetically distressing keloid growth attributed to the mammograms.
- Mammography involves repeated compression of breast tissue, potentially acting as a repetitive injury stimulus.
Findings:
- The study documents an unusual instance of keloid development directly linked to the mechanical stress of repeated mammography.
- The excessive keloid growth caused significant discomfort and aesthetic concerns for the patient.
- This suggests that mammography can, in susceptible individuals, induce an abnormal wound healing response manifesting as keloids.
Implications:
- Clinicians should consider the potential for keloid formation in patients undergoing frequent mammograms, especially those with a history of keloids.
- Further research is warranted to understand the specific mechanisms linking mammography to keloidogenesis.
- This finding may inform patient counseling regarding the risks and benefits of frequent breast imaging in predisposed individuals.
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