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Published on: October 27, 2023
Curcumin: Recent Advances in the Development of Strategies to Improve Oral Bioavailability
Katherine Z Sanidad1,2, Elvira Sukamtoh1, Hang Xiao1,2
1Department of Food Science, University of Massachusetts, Amherst, Massachusetts 01003, USA; email: mcclements@foodsci.umass.edu , guodongzhang@umass.edu.
Abstract:
Substantial human and preclinical studies have shown that curcumin, a dietary compound from turmeric, has a variety of health-promoting effects including but not limited to antioxidant, antimicrobial, anti-inflammatory, and anticancer actions. However, curcumin has poor bioavailability, and high doses of curcumin are usually needed to exert its health-promoting effects in vivo, limiting its applications for disease prevention. Here, we discuss the health-promoting effects of curcumin, factors limiting its bioavailability, and strategies to improve its oral bioavailability.
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Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...

