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Updated: Jan 30, 2026

Quantitative Analysis by Thermogravimetry-Mass Spectrum Analysis for Reactions with Evolved Gases
Published on: October 29, 2018
Thermal decomposition of vitamin C: An evolved gas analysis-ion attachment mass spectrometry study
Márta Juhász1, Yuki Kitahara1, Toshihiro Fujii1
1Department of Chemistry, Faculty of Sciences and Engineering, Meisei University, Hodokubo 2-1-1, Hino, Tokyo 191-8506, Japan.
Abstract:
Evolved gas analysis-ion attachment mass spectrometry (EGA-IAMS) was utilised to study the real-time non-isothermal decomposition of vitamin C. Dehydro-l-ascorbic acid, which has until this study been undetectable from the solid phase degradation of vitamin C, was observed as a decomposition product. While it is an important compound because it possesses some biological activity, dehydro-l-ascorbic acid is difficult to measure due to its chemical instability. In the present study using EGA-IAMS, we were able to detect dehydro-l-ascorbic acid from the thermal degradation of vitamin C. Our EGA-IAMS results obtained from the thermal decomposition of vitamin C were compared with a previous study employing pyrolysis-gas chromatography-mass spectrometry (Pyr-GC-MS). The observed quantitative and qualitative differences of the pyrolysis products obtained by the two techniques (EGA-IAMS vs. Pyr-GC-MS) are in part due to the difference in transportation time of the products out of the pyrolysis chamber.
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