Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

866
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
866
Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

Radiological Investigation II: MRI and Ventilation Perfusion Scan

605
Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
605
Biasing of FET01:22

Biasing of FET

707
Biasing a Junction Field Effect Transistor (JFET) is crucial for setting operational parameters and ensuring efficient functioning in electronic circuits. JFETs are characterized by using a single carrier type in N-channel or P-channel configurations, where the channel is surrounded by PN junctions. These junctions are central to the device's ability to control current flow.
In an N-channel JFET, the structure consists of N-type material forming the channel on a P-type substrate, with the...
707
Transcription Attenuation in Prokaryotes02:42

Transcription Attenuation in Prokaryotes

18.4K
Transcriptional attenuation occurs when RNA transcription is prematurely terminated due to the formation of a terminator mRNA hairpin structure.  Bacteria use these hairpins to regulate the transcription process and control the synthesis of several amino acids including histidine, lysine, threonine, and phenylalanine. Transcription attenuation takes place in the non-coding regions of mRNA.
There are several different mechanisms used to attenuate transcription. In ribosome mediated...
18.4K
Distance Corrections01:15

Distance Corrections

288
To achieve precise distance measurements, especially in surveying and construction, certain corrections must be applied to account for potential sources of error like the standardization errors, temperature variations, and slope adjustments.Standardization error emerges when measurement equipment undergoes changes, such as wear, repairs, or weather impacts. To address this, surveyors compare the equipment’s readings to a standard. This process identifies any deviation that might lead to...
288
Power Factor Correction01:20

Power Factor Correction

537
The power transmission to a factory involves the transfer of apparent power, a combination of active and reactive power. The power factor measures how effectively electrical power is converted into useful work output. The ratio of the real power (KW) that does the work to the apparent power (KVA) supplied to the circuit.
537

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Limitations in diagnostics and quantification of small lesions with low uptake in the clinical context of prostate <sup>18</sup>F/<sup>68</sup>Ga-PSMA PET/MRI.

EJNMMI physics·2026
Same author

Continuous infusion [<sup>11</sup>C]-(+)-PHNO PET for measuring dopamine D<sub>2/3</sub> receptor availability and amphetamine effects across the brain: Feasibility and test-retest reliability.

European journal of nuclear medicine and molecular imaging·2026
Same author

What you see is not always what you get-MRI-based ganglionic eminence volumetry challenges subjective assessment in CNS anomalies.

European radiology·2026
Same author

Prenatal alcohol exposure affects placental degradation-a retrospective fetal MRI study.

European radiology·2026
Same author

Active Brown Adipose Tissue Is Associated With Reduced Arterial Inflammation and Less Atherogenic Circulating Factors in Individuals With Obesity.

Arteriosclerosis, thrombosis, and vascular biology·2026
Same author

Phenotyping trisomies 13 and 18 and CHARGE syndrome in fetal MRI-a proposed phenome-based, morphological disease severity score, and network medicine analysis.

European radiology·2026
Same journal

Body composition's effect on the bone-vascular axis of osteoporosis discovered in AI-based CT analysis of COPD patients.

European radiology·2026
Same journal

ESR Essentials: pelvic floor imaging-practice recommendations by the European Society of Urogenital Radiology.

European radiology·2026
Same journal

STIR or T2-Dixon? A false dilemma in musculoskeletal MRI.

European radiology·2026
Same journal

ESR Essentials: uterine cancers-practice recommendations by the European Society of Urogenital Radiology.

European radiology·2026
Same journal

Adjunctive quantification for more reproducible amyloid PET interpretation.

European radiology·2026
Same journal

APEX-NET: automated pancreatic evaluation network using early non-contrast CT.

European radiology·2026
See all related articles

Related Experiment Video

Updated: Jan 30, 2026

Whole-body PET/MRI of Pediatric Patients: The Details That Matter
10:02

Whole-body PET/MRI of Pediatric Patients: The Details That Matter

Published on: December 19, 2017

15.3K

Dynamic [18F]FET-PET/MRI using standard MRI-based attenuation correction methods.

Ivo Rausch1, Andreas Zitterl2, Neydher Berroterán-Infante1

  • 1QIMP Team, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.

European Radiology
|January 13, 2019
PubMed
Summary
This summary is machine-generated.

Dynamic [18F]FET PET/MRI tumor grading is reliable with various MRI-based attenuation correction methods. Ensure accurate tumor delineation for consistent time-activity curve analysis in brain imaging.

Keywords:
Brain neoplasmsMagnet resonance imagingPositron emission tomographyRadionuclide imaging

More Related Videos

MRI and PET in Mouse Models of Myocardial Infarction
10:46

MRI and PET in Mouse Models of Myocardial Infarction

Published on: December 19, 2013

12.4K
Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451
05:17

Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451

Published on: April 18, 2025

929

Related Experiment Videos

Last Updated: Jan 30, 2026

Whole-body PET/MRI of Pediatric Patients: The Details That Matter
10:02

Whole-body PET/MRI of Pediatric Patients: The Details That Matter

Published on: December 19, 2017

15.3K
MRI and PET in Mouse Models of Myocardial Infarction
10:46

MRI and PET in Mouse Models of Myocardial Infarction

Published on: December 19, 2013

12.4K
Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451
05:17

Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451

Published on: April 18, 2025

929

Area of Science:

  • Neuroimaging
  • Radiochemistry
  • Oncology

Background:

  • Dynamic [18F]FET PET/MRI is crucial for brain tumor assessment.
  • Accurate attenuation correction (AC) is vital for quantitative PET analysis.
  • Different MRI-based AC methods may impact quantitative results.

Purpose of the Study:

  • To evaluate the influence of various MRI-based AC methods on tumor grading using dynamic [18F]FET PET/MRI.
  • To compare AC methods against CT-based AC as a reference standard.

Main Methods:

  • Dynamic [18F]FET PET/MRI scans were acquired in 24 patients with suspected brain tumors.
  • PET data were reconstructed using Dixon-based, ultra-short echo time MR-AC, and model-based AC methods.
  • Time-activity curves (TACs) and time to peak (TTP) were analyzed and compared to CT-based AC.

Main Results:

  • TAC patterns remained largely unchanged across different AC methods.
  • Minor changes in TAC patterns (up to 8%) and TTP (up to 17%) were observed.
  • These variations were primarily attributed to differences in region-of-interest (ROI) delineations.

Conclusions:

  • Dynamic [18F]FET PET/MRI with different MR-AC methods is suitable for assessing TAC patterns.
  • Accurate and visually validated tumor segmentation is essential for reliable analysis.
  • Consistent AC method application ensures reliable tumor grading.