Related Experiment Video
Updated: Jan 30, 2026
08:00
Studying Brain Function in Children Using Magnetoencephalography
Published on: April 8, 2019
9.6K
[Brain tumors in children: about 136 cases]
Fatima-Ezzahra Hazmiri1, Fatima Boukis1, Said Ait Benali2
1Service d'Anatomie Pathologique, CHU Mohammed VI, Hôpital Arrazi, Marrakech, Maroc.
The Pan African Medical Journal
|January 15, 2019
Summary
This study details pediatric brain tumor epidemiology in Marrakech, Morocco. Findings show infratentorial tumors and astrocytoma/medulloblastoma are most common, aligning with global trends.
Area of Science:
- Pediatric Oncology
- Neuro-oncology
- Epidemiology
Background:
- Brain tumors are the most common solid tumors in children globally.
- Limited data exists on pediatric brain tumor epidemiology and pathology in Africa, particularly Morocco.
Purpose of the Study:
- To describe the epidemiological and anatomopathological characteristics of primary brain tumors in children in Marrakech, Morocco.
- To compare findings with existing global literature.
Main Methods:
- Retrospective study of 136 pediatric patients diagnosed with primary brain tumors.
- Data collected from the Division of Anatomic Pathology, Mohammed VI University Hospital, Marrakech (2004-2016).
Main Results:
- A total of 136 cases were identified (mean 11.33/year), with a mean patient age of 8.28 years and a male predominance (M/F ratio 1.6).
- Infratentorial tumors (61.53%) predominated over supratentorial tumors (38.47%), frequently located in the cerebellar hemisphere.
- Astrocytoma (29.41%) and medulloblastoma (16.91%) were the most frequent histological types, accounting for 46.32% of all cases. Peak incidence was observed in children aged 5-9 and 10-15 years.
Conclusions:
- Pediatric brain tumor epidemiology in Marrakech shares similarities with North African and international data.
- This study provides crucial insights into the specific profile of pediatric brain tumors in southern Morocco, aiding in targeted research and clinical management.
Related Concept Videos
01:29Drug Dosing: Infants and Children
293
Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
293
01:27Tumor Immunotherapy
1.9K
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
1.9K
02:07Tumor Progression
7.4K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
7.4K
02:17The Tumor Microenvironment
7.8K
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
7.8K
01:23Brain Waves
4.1K
Brain waves are electrical signals generated by the neurons in the brain, which are regularly monitored to measure mental activities. Brain waves and their frequency ranges can be measured using an electroencephalogram or EEG. There are four main types of brain waves, each with distinct characteristics:
4.1K
01:30Organization of the Brain
2.7K
The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
2.7K