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High-Quality Draft Genome Sequence of Pseudomonas aeruginosa 268 Isolated from a Patient with a Left Ventricular

Logan J Voegtly1,2, Gregory K Rice1,2, Regina Z Cer1,2

  • 1Genomics & Bioinformatics Department, Biological Defense Research Directorate, Naval Medical Research Center, Fort Detrick, Maryland, USA.

Microbiology Resource Announcements
|January 15, 2019
PubMed

Insights

We present the genome sequence of Pseudomonas aeruginosa 268, a bacterium causing persistent bloodstream infections in patients with left ventricular assist devices (LVAD). This data aids in understanding and combating these difficult-to-treat infections.

Area of Science:

  • Microbiology
  • Genomics
  • Infectious Diseases

Background:

  • Pseudomonas aeruginosa frequently causes persistent bloodstream infections.
  • Left ventricular assist devices (LVAD) are associated with these difficult-to-treat infections.

Purpose of the Study:

  • To provide a high-quality draft genome assembly for a clinical isolate of Pseudomonas aeruginosa (P. aeruginosa 268).
  • To facilitate research into P. aeruginosa bloodstream infections related to LVAD.

Main Methods:

  • High-quality draft genome sequencing and assembly of the clinical isolate P. aeruginosa 268.

Main Results:

  • A high-quality draft genome assembly for P. aeruginosa 268 was successfully generated.
  • The genome sequence is publicly available in GenBank (accession number CP032761).

Conclusions:

  • The availability of this genome sequence provides a valuable resource for studying the genetic basis of P. aeruginosa infections in LVAD patients.
  • Further research can leverage this genomic data to develop targeted therapeutic strategies.

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