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Precision Psychiatry and Dual Disorders.

Nestor Szerman1, Lola Peris2

  • 1a Servicio de Psiquiatría , Hospital Universitario Gregorio Marañon , Madrid , Spain.

Journal of Dual Diagnosis
|January 15, 2019
PubMed
Summary

Precision psychiatry offers new insights into dual disorders, which involve addiction co-occurring with other mental health conditions. Understanding individual vulnerabilities is key to developing targeted treatments for addiction and co-occurring disorders.

Keywords:
Precision medicineaddictionco-occurring disordersdual disordersprecision psychiatry

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Area of Science:

  • Neuroscience and Psychiatry
  • Addiction Research
  • Precision Medicine

Background:

  • Addiction frequently co-occurs with personality traits, psychiatric disorders, and cognitive impairment, collectively termed dual disorders.
  • The high co-occurrence suggests underlying causal links and shared neurobehavioral mechanisms.
  • Individual responses to substances vary significantly, influenced by factors including sex.

Purpose of the Study:

  • To review the concept of precision psychiatry in the context of dual disorders.
  • To explore neurobiological perspectives on addiction, dual disorders, and precision medicine.
  • To identify advancements and future research directions for precision psychiatry in dual disorders.

Main Methods:

  • A state-of-the-art review of the literature was conducted.
  • The PubMed database was searched for articles published in the last 15 years.
  • Keywords included dual disorders, addiction, mental disorders, precision medicine, and precision psychiatry.

Main Results:

  • Significant progress has been made in understanding addiction and dual disorders.
  • Precision medicine aims to identify individual vulnerabilities to illness and treatment response.
  • Advances in precision medicine for addiction require identifying biological and environmental factors contributing to vulnerability and treatment moderators.

Conclusions:

  • Precision psychiatry offers a novel framework for understanding and addressing dual disorders.
  • Future research should focus on discoveries, research directions, and translational relevance.
  • This approach may provide new perspectives on the nature and treatment of dual disorders.