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Updated: Jan 30, 2026

Influenza A Virus Studies in a Mouse Model of Infection
Published on: September 7, 2017
[Influenza infection: An update for clinicians]
M Blot1, P Chavanet2, L Piroth2
1Département de maladies infectieuses et tropicales, CHU François-Mitterrand, 21000 Dijon, France; Inserm UMR 1231, Lipides/Nutrition/Cancer, université Bourgogne-Franche-Comté, 21000 Dijon, France.
Abstract:
Lower respiratory infections remain the deadliest communicable disease in the world. Influenza infections are particularly involved, whether intrinsically, or more frequently, by promoting bacterial infections and superinfections. The flu is also responsible for the decompensation of many comorbidities and could lead to some myocardial infarction and stroke. The effect of antiviral therapies is limited but preventives measures, such as vaccination, remain a major public health issue. The flu is a major challenge at all levels and all times, from vaccine prevention, to the recognition of atypical forms, and the early management of bacterial complications.
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