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HIIT Improves Left Ventricular Exercise Response in Adults with Type 2 Diabetes
Genevieve A Wilson1, Gerard T Wilkins1, Jim D Cotter2
1Department of Medicine, University of Otago, Dunedin, NEW ZEALAND.
Medicine and Science in Sports and Exercise
|January 15, 2019
Summary
High-intensity interval training (HIIT) improved left ventricular function in adults with type 2 diabetes. This exercise intervention enhanced stroke volume and left ventricular filling and emptying during physical activity.
Area of Science:
- Cardiology
- Exercise Physiology
- Diabetology
Background:
- Type 2 diabetes is linked to diminished left ventricular reserve.
- The impact of exercise training on left ventricular function in type 2 diabetes remains unclear.
Purpose of the Study:
- To investigate if 3 months of high-intensity interval training (HIIT) enhances left ventricular function during exercise in type 2 diabetes patients.
Main Methods:
- Assessed V˙O2peak, body composition, and total blood volume.
- Measured left ventricular volumes (LVEDV, LVESV) and stroke volume (LVSV) at rest and during exercise.
- Compared HIIT (n=11) versus a control group (n=5) over 3 months using ANOVA.
Main Results:
- HIIT significantly increased V˙O2peak by ~15% without altering body composition or blood volume.
- HIIT enhanced left ventricular end-diastolic volume (LVEDV) and left ventricular stroke volume (LVSV) across all exercise intensities.
- HIIT improved the reduction in left ventricular end-systolic volume (LVESV) during exercise, unlike the control group.
Conclusions:
- High-intensity interval training (HIIT) augments exercise-induced left ventricular stroke volume response in type 2 diabetes.
- HIIT shows potential to improve cardiac function, specifically left ventricular filling and emptying, during exercise.
- These findings suggest HIIT may reverse early cardiac impairments associated with type 2 diabetes.
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