Related Experiment Video
Updated: Jan 30, 2026

04:51
Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy
Published on: April 11, 2019
10.4K
[Electroconvulsion therapy for persistent depression in the Netherlands; very low application rate]
Tijdschrift Voor Psychiatrie
|January 15, 2019
Summary
Electroconvulsive therapy (ECT) is underutilized in persistent depressive disorder, with only 1.2% of eligible patients receiving it in the Netherlands. This suggests potential gaps in knowledge or application of this potent depression treatment.
Area of Science:
- Psychiatry
- Clinical Psychology
- Health Services Research
Background:
- Persistent depressive disorder affects 20% of all depressive disorders and is often treatment-resistant.
- Electroconvulsive therapy (ECT) is the most potent treatment for severe depression.
- Dutch guidelines recommend ECT for persistent depression after 12 months of inadequate treatment.
Purpose of the Study:
- To quantify the utilization of electroconvulsive therapy (ECT) in persistent depressive disorder patients in the Netherlands.
Main Methods:
- Quantitative research utilizing the Dutch diagnosis-treatment-combination (DBC) information system (DIS).
- Data sourced from the Dutch Healthcare Authority (NZa) for the year 2014.
- Analysis focused on patients diagnosed with unipolar depression for over two years.
Main Results:
- In 2014, 23,597 patients (26%) with unipolar depression had a persistent depressive episode.
- Only 278 patients (1.2%) from this persistent depression group received ECT.
- A significant disparity exists between the number of patients eligible for ECT and those who received it.
Conclusions:
- ECT is significantly underused in the Netherlands for persistent depression, with only 1.2% of eligible patients receiving it.
- The low application rate may stem from insufficient professional knowledge of ECT or premature use of the handicap model.
- Further investigation into barriers preventing ECT use is warranted to improve patient outcomes.
Related Concept Videos
Electroconvulsive Therapy
1.1K
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
1.1K
Application of Rates of Change
485
The movement of a car along a highway can be examined through key principles of calculus and kinematics. As the car travels, its position varies over time and can be represented mathematically as a function of time. Analyzing the rate of these changes enables the measurement of velocity and acceleration, fundamental aspects of motion analysis.Velocity describes how position changes over time. The average velocity during a specific time interval is calculated by dividing the change in position...
485
Long-term Depression
33.3K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
33.3K
Long-term Depression
3.4K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
Calcium Ion Concentration Mechanism
If over...
3.4K
Freezing Point Depression and Boiling Point Elevation
40.0K
Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
40.0K
Depressants
428
Depressant drugs, including alcohol and sedative-hypnotics, diminish central nervous system activity by enhancing the action of gamma-aminobutyric acid (GABA), a neurotransmitter that reduces brain activity and promotes relaxation. These substances can have various therapeutic uses but also pose significant risks, especially when misused or combined.
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
428

