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Updated: Jan 30, 2026

Whole-Body Nanoparticle Aerosol Inhalation Exposures
Published on: May 7, 2013
Performance evaluation of disposable inhalable aerosol sampler at a copper electrorefinery
Eun Gyung Lee1, Peter J Grimson2, William P Chisholm1
1a National Institute for Occupational Safety and Health (NIOSH) , Health Effects Laboratory Division, Exposure Assessment Branch , Morgantown , West Virginia.
The disposable inhalable aerosol sampler (DIAS) shows higher copper exposure results than the IOM sampler for area measurements, but personal exposure results were inconclusive. Further studies are needed to evaluate DIAS performance across various elements.
Area of Science:
- Occupational Health and Safety
- Environmental Monitoring
- Industrial Hygiene
Background:
- Traditional inhalable particle samplers can be costly.
- A new, cost-effective disposable inhalable aerosol sampler (DIAS) has been developed.
- Evaluating new sampling technologies is crucial for accurate exposure assessment.
Purpose of the Study:
- To evaluate the performance of the disposable inhalable aerosol sampler (DIAS) against the established IOM sampler.
- To compare copper exposure measurements collected by DIAS and IOM samplers in an electrorefinery.
- To assess the reliability and potential biases of the DIAS for occupational exposure monitoring.
Main Methods:
- Forty-eight pairs of DIAS prototypes and IOM samplers were used for personal and area sampling.
- Copper exposure measurements were collected at an electrorefinery facility.
- Statistical analyses, including geometric mean ratios and concordance correlation coefficients, were performed.
Main Results:
- The geometric mean ratio of DIAS/IOM was 1.1 for personal and 1.6 for area sampling.
- Significant disagreements were found between DIAS and IOM samplers, attributed to precision issues.
- DIAS yielded higher mean concentrations than IOM for area exposures (p < 0.05), but results were comparable for personal exposures (p = 0.49).
Conclusions:
- The DIAS shows potential for cost-effective inhalable aerosol sampling but requires further validation.
- Performance differences between DIAS and IOM samplers were observed, particularly for area measurements.
- Particle migration during sample transport was noted for both samplers, highlighting potential error sources.
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