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[Effect of Transcutaneous Acupoint Electrical Stimulation on Propofol Usage in Closed-loop Anes- thesia Delivery

Ning Jin, Yan-Chao Yang, Xiu-Fei Teng

    Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine
    |January 15, 2019
    PubMed

    Insights

    Transcutaneous acupoint electrical stimulation (TEAS) reduced propofol usage and improved hemodynamic stability in pediatric patients undergoing surgery. TEAS also decreased stress and inflammatory responses, leading to better outcomes.

    Area of Science:

    • Anesthesiology
    • Pain Management
    • Integrative Medicine

    Background:

    • Pediatric anesthesia requires careful management of hemodynamics and stress response.
    • Closed-loop anesthesia systems aim for precise drug delivery but may need adjunctive therapies.
    • Transcutaneous acupoint electrical stimulation (TEAS) is a non-invasive technique with potential analgesic and anti-inflammatory effects.

    Purpose of the Study:

    • To evaluate the impact of TEAS on propofol consumption in a closed-loop anesthesia system.
    • To assess the effects of TEAS on hemodynamic parameters in pediatric surgical patients.
    • To investigate TEAS's influence on stress and inflammatory markers, and post-operative recovery.

    Main Methods:

    • A randomized controlled trial involving 60 pediatric patients undergoing tonsillectomy/adenoidectomy.
    • Patients were assigned to either TEAS or a control group receiving standard anesthesia.
    • Hemodynamic parameters, propofol dosage, stress hormones (epinephrine), inflammatory cytokines (IL-1, IL-6), and pain/delirium scales were monitored.

    Main Results:

    • The TEAS group showed significantly reduced mean arterial pressure and heart rate fluctuations.
    • TEAS led to a significant decrease in total propofol dose and adjustment frequency.
    • Reduced levels of epinephrine, IL-1, and IL-6 were observed in the TEAS group, alongside lower pain and emergence delirium scores.

    Conclusions:

    • TEAS effectively stabilizes pediatric hemodynamics during surgery.
    • TEAS reduces the need for propofol in closed-loop anesthesia systems.
    • TEAS mitigates stress and inflammatory responses, improving post-operative outcomes in children.

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