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Updated: Jan 30, 2026

Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus
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Genome Sequences of Livestock-Associated Methicillin-Resistant Staphylococcus aureusspa Type t899 Strains Belonging

Henok Ayalew Tegegne1,2,3, Ivana Koláčková1, Martina Florianová1

  • 1Department of Bacteriology, Veterinary Research Institute, Brno, Czech Republic.

Microbiology Resource Announcements
|January 16, 2019
PubMed

Insights

Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) is a growing threat. This study presents genome sequences of nine LA-MRSA strains from meat and humans, revealing genetic diversity within this emerging pathogen.

Area of Science:

  • Microbiology
  • Genomics
  • Public Health

Background:

  • Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) represents an emerging pathogen lineage.
  • LA-MRSA is rapidly evolving and increasingly detected in community settings.

Purpose of the Study:

  • To present the draft genome sequences of nine LA-MRSA strains.
  • To characterize the genetic relatedness and diversity of these strains.

Main Methods:

  • Whole-genome sequencing of nine LA-MRSA isolates.
  • Bioinformatic analysis including spa typing and sequence typing (ST).

Main Results:

  • Nine LA-MRSA strains were sequenced, isolated from meat and a human nasal swab.
  • All strains belonged to a single unique spa type (t899).
  • However, the strains represented three distinct sequence types: ST398, ST9, and ST4034.

Conclusions:

  • The genetic diversity of LA-MRSA is highlighted by the presence of multiple sequence types within a single spa type.
  • Understanding the genomic landscape of LA-MRSA is crucial for tracking its evolution and spread.

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