Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Yeast Signaling01:28

Yeast Signaling

Yeasts are single-celled organisms, but unlike bacteria, they are eukaryotes (cells with a nucleus). Cell signaling in yeast is similar to signaling in other eukaryotic cells. A ligand, such as a protein or a small molecule released from a yeast cell, attaches to a receptor on the cell surface. The binding stimulates second-messenger kinases to activate or inactivate transcription factors that further regulate gene expression. Many of the yeast intracellular signaling cascades have similar...
Imprinting01:22

Imprinting

Behavioral imprinting is observed in some newborn animals and occurs when they develop strong and specific attachments to another animal (usually a parent) following brief, early-life exposures. Offspring imprint onto parents within a brief period after birth or hatching; this time window is called the critical period. Once imprinting occurs, the bond established between the parents and their offspring is usually long-lasting.
Bioreactor Controls-III01:22

Bioreactor Controls-III

Strain improvement is a foundational strategy in industrial microbiology aimed at maximizing microbial productivity, particularly because natural isolates typically yield commercially valuable products in very low concentrations. Although optimizing the culture medium and environmental conditions can improve yields, these adjustments are inherently limited by the organism’s genetic potential. As a result, the focus shifts toward genetic modifications to enhance biosynthetic capacity. The...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

DNA transposon expansion drives genome plasticity in Diutina catenulata.

Nature communications·2026
Same author

Towards the construction of a virtual yeast.

Nature·2026
Same author

The genetics of the many forms of diversity.

Genetics·2026
Same author

Microbial domestication: Farmhouse brewing preserves a hidden reservoir of yeast diversity.

Current biology : CB·2026
Same author

Population-scale chemical response revealed by a barcoded yeast collection.

Nature communications·2026
Same author

The adaptive molecular landscape of reprogrammed telomeric sequences.

Nature communications·2026

Related Experiment Video

Updated: Jun 3, 2026

Yeast Colony Embedding Method
09:04

Yeast Colony Embedding Method

Published on: March 22, 2011

André Goffeau's imprinting on second generation yeast "genomologists".

Cécile Fairhead1, Gilles Fischer2, Gianni Liti3

  • 1UMR Génétique Quantitative et Evolution - Le Moulon, INRA - Université Paris-Sud - CNRS - AgroParisTech, Orsay, France.

Yeast (Chichester, England)
|January 16, 2019
PubMed
Summary

The Saccharomyces cerevisiae genome project revolutionized yeast genomics, enabling studies on eukaryotic processes and the evolutionary history of yeast populations. This work highlights advances in comparative and population genomics stemming from this foundational effort.

Keywords:
André GoffeauSaccharomyces cerevisiaegenome sequencegenomics

More Related Videos

High Throughput Yeast Strain Phenotyping with Droplet-Based RNA Sequencing
07:55

High Throughput Yeast Strain Phenotyping with Droplet-Based RNA Sequencing

Published on: May 21, 2020

In Vivo Monitoring of Transcriptional Activity During Metabolic Transition Using a Bioluminescent Reporter in Yeast
06:53

In Vivo Monitoring of Transcriptional Activity During Metabolic Transition Using a Bioluminescent Reporter in Yeast

Published on: February 21, 2025

Related Experiment Videos

Last Updated: Jun 3, 2026

Yeast Colony Embedding Method
09:04

Yeast Colony Embedding Method

Published on: March 22, 2011

High Throughput Yeast Strain Phenotyping with Droplet-Based RNA Sequencing
07:55

High Throughput Yeast Strain Phenotyping with Droplet-Based RNA Sequencing

Published on: May 21, 2020

In Vivo Monitoring of Transcriptional Activity During Metabolic Transition Using a Bioluminescent Reporter in Yeast
06:53

In Vivo Monitoring of Transcriptional Activity During Metabolic Transition Using a Bioluminescent Reporter in Yeast

Published on: February 21, 2025

Area of Science:

  • Genomics
  • Molecular Biology
  • Evolutionary Biology

Background:

  • Saccharomyces cerevisiae is a model organism for genetics and eukaryotic cellular processes.
  • Historically, knowledge of yeast natural and evolutionary history was limited.
  • The sequencing of the S. cerevisiae reference genome provided a foundation for further research.

Purpose of the Study:

  • To describe recent advances in yeast comparative and population genomics.
  • To highlight the impact of the S. cerevisiae genome project on yeast research.
  • To explore the origins of these advances in the work initiated by André Goffeau.

Main Methods:

  • Comparative genomics analysis
  • Population genomics studies
  • Leveraging the S. cerevisiae reference genome data

Main Results:

  • Significant progress in understanding eukaryotic biological processes.
  • Foundation laid for studying genome and ecological diversity of yeast populations.
  • New insights into the natural and evolutionary history of yeasts.

Conclusions:

  • The S. cerevisiae genome project was pivotal for modern yeast genomics.
  • Comparative and population genomics have expanded our understanding of yeast diversity.
  • Continued research builds upon the foundational genomic data of S. cerevisiae.