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Discriminating Seebeck sensing of molecules
1Physics Department, Lancaster University, Lancaster LA1 4YB, UK. h.sadeghi@lancaster.ac.uk.
Physical Chemistry Chemical Physics : PCCP
|January 17, 2019
Summary
Seebeck coefficient sign changes can detect specific molecules. This method overcomes variability issues in molecular sensors, enabling new gas and biomolecule detection strategies.
Area of Science:
- Molecular electronics
- Nanoscale sensing
- Thermoelectric effects
Background:
- Molecular-scale sensors face junction-to-junction variability, impacting electrical conductance measurements.
- Seebeck coefficient measurements in molecular junctions exhibit smaller variations and resilience to conformational changes.
Purpose of the Study:
- To demonstrate the utility of the Seebeck coefficient's sign for discriminating molecular sensing.
- To explore the application of Seebeck sensing for detecting gas and biomolecules.
Main Methods:
- Utilizing metalloporphyrin molecular wires for thermoelectric measurements.
- Analyzing changes in the Seebeck coefficient sign upon interaction with cytosine nucleobases and chlorine gas.
Main Results:
- A positive Seebeck coefficient sign shifted to negative upon absorption of cancerous cytosine nucleobases.
- Interaction of chlorine gas with Mn-porphyrin molecular wires induced a sign change in the Seebeck coefficient.
- Observed sign changes are attributed to spin-driven bound states near the Fermi energy.
Conclusions:
- The sign of the Seebeck coefficient serves as a robust feature for molecular sensing.
- Seebeck sensing offers a novel and versatile approach for detecting various molecules, including gases and biomolecules.
- This generic sensing concept holds significant potential for future applications in molecular diagnostics and environmental monitoring.
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