Material and Structural Modeling Aspects of Brain Tissue Deformation under Dynamic Loads

The aim of this work was to assess the numerous approaches to structural and material modeling of brain tissue under dynamic loading conditions. The current technological improvements in material modeling have led to various approaches described in the literature. However, the methods used for the determination of the brain's characteristics have not always been stated or clearly defined and material data are even more scattered. Thus, the research described in this paper explicitly underlines directions for the development of numerical brain models. An important element of this research is the development of a numerical model of the brain based on medical imaging methods. This approach allowed the authors to assess the changes in the mechanical and geometrical parameters of brain tissue caused by the impact of mechanical loads. The developed model was verified through comparison with experimental studies on post-mortem human subjects described in the literature, as well as through numerical tests. Based on the current research, the authors identified important aspects of the modeling of brain tissue that influence the assessment of the actual biomechanical response of the brain for dynamic analyses.